Is a chronic inflammatory dystrophic diffusive injury of liver of different nature, which has lasted for more than six months and ischaracterized by different degree of necrosis of the liver cells.
The most widely spread reason of the chronic hepatitis is viral hepatitis (from which the patients had suffered before). The virus may enter the blood while blood transfusion, insufficient sterilization of medical instruments, through contaminated needles or through sexual intercourse.
Nowadays there are seven types of the virus hepatitis – A,B,C,D,E,F,G. Chronic form is usually identified in cases of B,C,D forms of hepatitis. Hepatitis C, is the most frequent one.
The cases are especially severe, when the patients are affected by two types of hepatitis, such as D and B. Factors that affect the severity of the condition depend upon immune deficiency and dysfunction of cellular immune system. These may be considered to be predisposing factors for the development of chronic hepatitis.
Main characteristics of the affected liver:
- The virus reproduction causes the development of certain amount of antigens. This process is accompanied by the activation of immune reaction, injury and death of cells.
- In addition to the anti-genes, anti-bodies are also developed. The anti-genes and anti-bodies form immune complexes, which are led out of the organism. This stimulates the activation of enzymes and the development of the of the tissue inflammation.
- The immune dysfunctions lead to the development of the thrombosis and dysfunctions in the system of blood coagulation. Micro-thrombosis is usually accompanied by micro-necrosis – this is considered to be the secondary inflammation.
Unlike other chronic hepatitis viruses, alcoholic hepatitis is the result of toxic affection of the liver. The degree of pathologic changes is directly linked to the duration and severity of alcoholic dependence. Liver overworks about 90% after ethanol; during this process acetaldehyde - a highly toxic substance is produced. As a result, the necrosis of the hepatocyte. Apart from alcohol, chronic hepatitis may the result of some other toxic substances, such as carbons, dichloromethane, chloroform, etc.
The Ozone has a pernicious influence on viruses, which destroy the receptors of the cells and this prevent them from attaching to the liver cells. As a result the virus is not able to enter the cell and the circle of its reduplication is interrupted. The reduplication process is also interrupted by Ozone splitting, which in its turn destroys the genetic apparatus of the virus.
The cells that have already been affected by the virus, are less resistant to the Ozone influence in comparison with healthy cells. These weak cells are destroyed by high concentrated Ozone, as well as the virus, and are led out of the organism. The Ozone enhances the antiviral immunity of the organism, activates its cellular and antibody response (the development of antibodies). Under the influence of Ozone, blood cells (lymphocytes and monocytes) produce more cytokines, and first of all interferon – one of the most important factors of inner protection of the organism against virus infections. All the stated above contributes to suppression and liquidation of the inflammatory process.
In the majority of cases for chronic hepatitis treatment, intravenous physiological solutions enriched with Ozone are injected. The intravenous physiological solutions may be substituted by rectal introduction of the Ozone or by auto-transfusion with Ozone (8-10 treatments only).
For the purpose of chronic hepatitis treatment,Ozone Therapy may be used on its own, or accompanied by other medical ways of treatment. The healing properties of Ozone Therapy, help to reduce the use of highly expensive medicines.